up against this weird formation

[NicolasFC]

5-1mc-2aml/amr- 2st. How should i set my team up

I don't have the answer to your question but played a match today against 5 - 2 - 1 - 1 - 1 .
I know it's not the same formation exactly but this might help you.

This was the first game I did not win since the begining of the season, so I guess this means he will be very strong in defense.
The tip for this is that most of my attacks were cut by his 2 DMCs and his DL, DR. So if I were you I would put some AMC and more than 1 striker without forgetting to put some defense on the wings to avoid him to score (DR, DL, or DMR, DML) from his AMR-AML.

I focused attacking from both flanks with hard attacking , own side , mixed. He had 2 or 3 goal opportunities in the whole game against 20+ of mine. As I said before his DMCs did a fine job so having your opponent with no player in that space my opinion wd be to put some player there.

Good luck!!