For 4-1-4-1 go défensive, counter attacks, hard tackling own half, long balls..
Ur formation looks good also as it uses amc and he doesn't have dmc..
I've played 3-5-2V and 4-5-1V against 4-3N-3, went down both flanks attacking hard tackling whole pitch, with good results.. It all depends if he's better then u or the opposite.. Do u need to defend and hit on the counter or u can attack?