hi welcome to the forum

Firstly ... I don't play football or play other management games (you need 48 hrs in a day to play some of them properly), and I haven't been playing this game very long ... so please feel free to ignore whatever else I say
but
imo

You've got all your defensive players pressing backwards and all your attacking players pressing forwards ... it's leaving a big gap in the centre of midfield and that must be costing you procession and the ability of your team to create chances.

Next .. you're focusing your passing through the middle, but pressing forward with a ML and MR, you need to bring these two players into the game more .. mixed passing at least.

Next .. and this is just my personal view ... but I don't like a dmc mc amc line in the middle, I personally feel that two mc's and either an amc or a dmc is a better option... but everyone sets their own teams up differently, their are no rights or wrongs on that.

Finally tell your players to get stuck in more .. easy tackles in a league/cup game . nope .. not for me .. get your players tackling normally ... makes no difference to the amount of injuries you get.

Just really experiment and find what works best for you, and then build on any successful tactics you find, and adapt when and if they go wrong . But above all have fun with it all.

Just my thoughts