3N-5V-2 works most of the time. Two seasons ago I lost 2 matches with 3N-5V-2 (normal, mixed poassing down both flanks, own half pressing) against 4-1-2-1-2s (equal level to 1* lower quality). The opponents probably played weird versions of it (red arrows on wing backs, long passing down both flanks or something like this), but against the standard version your system works.
I play most of the times assymetric systems when facing it now.