Some updates: Was too tired, slept pass the starting time and had my team at 4-1-2-1-2ND during start with 80-90% condition (last match was before I slept).
Best re-shuffling of formation i could go was for a 4-2-2-2 HEX during half time. Opponent scored 1-0 when I was still on ND, we even the score at 1-1 after I came on with HEX.

So I guess HEX would be the way to go vs 3N-2W-3N-2.
Wanted to try 3N-5-2 though, but my reserves were lacking ML and MRs since I overslept.