I think it depends all on your player. You know them, you know, which position is best for them.
F.E. I have an AML/AMC/AMR and he only performs on AMR well.
yes, that's very important.
Also important it's the quality of the two teams.
If oppo is equal or weaker, 3D (wide) + 1DMC
if oppo is stronger, you need
3D (w) + 2DMC,
or
4D +1DMC.
For attack, whatever is working better for your players.