Took me more than a couple of seasons to realize that no one plays against their scheduled opponent. Rather, you play against the programmed rules in the Game Engine (for that season).... so if Nordeus decide that in a particular season , weaker teams in a match have a default advantage (read: posession, goals, shots etc ...)... you could have all 9* players and get screwed anyway..

(Impossible) Trick to success would be to figure out (guess) what sadistic rules would drive the engine for next season. Having said that some tips (based on current season)

1.Weaker teams have the definite (dominant) advantage... Sell all your stronger players or rest them for big matches
2. DON'T BUY SCOUTS!! - OR even spend ridiculous amounts of tokens on transfers / auctions
3. PLAY Illegal formations - dosent dampen your chances of losing and you frustrate the hell out of your opponent , just for laughs
4. Don't watch any live matches - definitely improves winning chances
5. All else failing, "friend" everyone you are supposed to play with - and randomly schedule Friendly matches between 30 to 60 minutes before your actual match (dont forget to use Full pitch pressing and Hard tackling)