What affects the end result most?

[BigB79]

I think the players and also their stats (striking abilities for strikers, defending for defenders etc) is the most important factor. The formation, orders and possession are important as well. Then there is a luck factor.

I prefer using balanced 4-4-2 classic, because my players are well suited for it and it works often. When I want to defend or attack more, I can easily make some changes.

Hate to tell you but formations, orders and possession mean absolutely nothing in this game and people on this forum have proved that a number of times.