Precisely. I never lost against the mighty 4-5-1 v style . When i played against this formation ive always used 4-3-1-2 with short passing through the middle , pressing style whole pitch and counter attacks and it worked just fine for me . for ex last season in the Cl semi finals i won against 4-5-1 v style with a crashing 4-0 ,2 at home 2 away. Like maxtax said above it depends on your players skills and special atributes.