(With apologies to a UK Channel 4 TV programme)
Rotation, rotation, rotation...
If you get the mix of players right then you can play one, two or three lower-Q players in with the 'first team' for tougher matches without affecting performance and outcome, leaving the big guns to bolster the 'second team' in easier matches.
You'll need to do your research on your opponents to find out those positions that are vulnerable to being faced by a lower-Q player in your squad.