You should also consider that wingers (ML MR AMR AML) are the most inform players in the game. They are the main source of goals for most players so the fact that you can't stop them all the time shouldn't concern you since it is impossible to demand to never concede a goal.

Judging by your question I assume the only flank players you have are the 2 defenders DL and DR and yes that means you will be prone by teams that play down both flanks with skilled wingers.