Well, if you use 3 MC's, you will gain and avantage controlling the center of the pitch, you could add a red arrow on you CMC to support your 2 ST's. If you go wide with a MR, MC and a ML you may loose the center but gain the advantage on your wings when you add two red arrows to your MR and ML to support your 2 ST's.

If quality is equal, use zonal marking. I hope that this helps.