I don't think through the middle is a good idea. You have two wingers, use them. I would say down both flanks or mixed. Don't put red arrow on your DMC because 41212 has an AMC, if your DMC pushes high up in the pitch his AMC will play free without being pressed. Then in front of your GK there will be 3 (him with 2 ST + 1 AMC) versus 2 (you, 2 DC) situation.

Let us know how it went and what strategy you have used, it will surely help other users in any case.