I would go 4-1-2-1-1 ND, but then again, results varies. I've seen 80% of the time ND wins in my leagues, but then there's the 20% who somehow draw or loss badly. Fortunate for me, I've won all with only 1 draw with 4-4-2.
Do try it on a friendly to test it out. I go for Attack, Pass through the middle, Short pass, normal tackle, own half (full pitch if I'm still not scoring), zonal marking.
Red arrows on DL, DR, DMC and AMC. Blue on both DC.