Completely agree with Nick. I played 4-5-1 V for the last 6 seasons, won 2 cups, 4 CL, 1 treble and all the leagues but my strikers are just hopeless. They score every 4 or 5 games when my AM are unstoppable. DMC is also very important and if you are lucky enough to get a great MC (which happened to me last season with this 29 years old scout), no one should stop you. 4-5-1 V is basically a defensive formation and I barely concede 10 goals per league.