Ok, Abhi (and all)
That's one of the "mystery" formations of TE 3DC-DML-DMR-3MC-2ST
No counter as there is a solid defense from the middle and the flanks of defense, probably playing with defense counters and could be tricky sometimes if oppo uses red arrows for DML-DMR.
Usually what I do first, is to check his DML & DMR.
What positions are they playing ? Are the also DML-ML-AML ? or just DL-DML ? In the first case I must be careful because he could switch them to wingers or setting red arrows, performing like that. Also checking their stats (do they have many goals or assists ? ). In that case I prefer to use DR &DC watching also the wings of my defense.
If they are DL-DML, I prefer to use 3DC +1DMC and use another player as MC or AMC or 2nd ST.
Also prefer to play with defense/counter as attacking can cause opponents successful counters.
But all above are just tips and usually can't help playing vs that formation.
My experience so far, is that it's just a personal battle of my wingers vs oppo DML-DMR.
If my wingers are in a good day and win the duels, I 'll win.
Two games of this season for example
1) First league round : Playing home, oppo wasn't watching, his (her) defense was solid as a rock were my wingers crushed on.
Click image for larger version.  Name: 6 league game d6 lost.jpg  Views: 30  Size: 63.9 KB  ID: 67176

2) Second game of the league, today.
I was out and didn't watch so I just set a 4-5-1V, defense/counter, mix and normal all the others.
My wingers had a great day, her defenders not, and a domination came.
Click image for larger version.  Name: 23 VS CHRISTINA 0-5.jpg  Views: 28  Size: 68.8 KB  ID: 67177


What do I think ?
It's just a matter of a good day/bad day.