I played against 4-4-2 today (CL), he was 6% stronger. I started with 4-1-4-1 (def, middle, long, counters), but he had a way better stat and scored. In the 2nd half I switched to ND (normal, middle, long, counters off) and won 2-1. His SoT stayed a little bit better, but not that much as in the 1st half.