Ive been playing 3N-1-4-1-1 for a few seasons now.
Alternate between AMC-ST and 2 ST depending on opposition formation (whether he has a DMC or not).
Have had success against 4-3W-3 using it.
But, with any formation having 3ST, Ive had some problem in conceding from corners.
So, you can go with 3N-1-4-1-1, so long as the 3DCs and DMC are good at heading.
This is needed to ward off the threat from wings too.