Each formation has its strength and weakness, as always.
4-3-1-2 will lose to most opponent formations with 4 midfielders. 1AM + 2ST would be easily handled by 3 flat defenders + DMC as well.
This is good if opponent is only playing a 2-MCs midfield, and also good if opponent has no DMC.
Winning is a form of art. Consistently winning is a show-hand of skills and luck.