4-5-1v and 4-4-2 are my favorite formations, 4-5-1v in defense with long-pass / flank / half-pitch and force counter, 4-4-2 in normal default.
in 4-5-1v case, my mc(s) are aimed only to gain the cards... and sometimes goals in free-kick/corner, not prolific.
but in 4-4-2 case, the same MC are much powerful performance

So I just think, the performance affect maybe more in formation and suitable(if exist..)