I use this alot because I like my DMC and AMC. This is a very strong formation. My team is usually always superior so I play as follows :

attacking mentality
mix passing
short passing
whole pitch
offside trap
no counter

I always gain alot of possession playing this. However I avoid using this if I'm up against 4-2-2-2 hexagon or the butterfly because they will use fullbacks to overlap the attacking midfielders down the wing. This is especially strong against 3 ST if you're up against 4-3-3. With 6 midfielders you control a lot of the ball and do much damage. Most of the time I put red arrows on ML/MR and I like it better than using AMR/AML. Also my 2 wingers are very good in defensive abilities as well incase they need to track back and protect the wings. This is by far my most favourite formation. Check out my team and see more details.