4-4-2 with mr and ml or with AML and AMR?
First case 4-3-1-2 always pay me lot of dividend (set play through the middle). In second case I use 4-2-3-1, (set mix passes).
Against 4-2-3-1 generally I use 3 (DL-DC-DR)-1-2-3-1 (set mix passes). the other tacticts depends on strong of his defenders/attackers and style of play.