You are countering this formation?
DL-------DC-------DR
--------DMC---------
-----MC------MC-----
AML--------------AMR
-----ST------ST-----
His DMC won't be hard defending (most likely) since he has a DC right behind him, so a single striker formation should work. You will want to attack down the middle and defend flanks. So I'm thinking 4-4-1-1 or 4-3W-2-1. Both are more midfield heavy since AML/AMR are counted as "wing". The 4-3W-2-1 should use a blue defense arrow on the MC and neutral everywhere else and 4-4-1-1 is a little more risky since you will be defending two strikers.
Another option is 4-2N-2W-1-1 neutral arrows and attack down the flanks. I took this option in a friendly against 4-2-2-2 Hexagon with good success (very comparable since it's just motivating a DC to DMC).