The 3-2-2-1-2 with man-to-man marking would be an option if OP needed to contain his opponent and protect the lead, but he is ahead on Quality so 4-1-2-1-2 ('Narrow Diamond') with zonal marking and attack through the middle would be my choice in this situation.
Beware of starting with whole pitch and hard tackling, both will drain condition and make you vulnerable to injury in the first instance and yellow cards in the second - as well as pi---, er, upsetting the Assistant Manager...