U can even play 4-2-2-2 if u feel that one striker up front won't perform well.this can be done by removing an MC and making him striker in 4-3n-2w-1 formation.the only difference when u do this is that u will have one player less in midfield making it ur 2 central midfielder vs his 1 central midfielder and that u will have good scoring opportunities with 2 strikers