He'll have to replace one of his strikers with another midfielder if he is to use forward runs on the full backs AND wide midfielders.
I don't think so. If he has good fullbacks he can red them in a 4-4-2 variation. 2 DMCs controll midfield quite well when fullbacks + wingers run forward. He always defends with 5+ even if he is counterattacked.
A football team is like a beautiful woman. When you do not tell her, she forgets she is beautiful