I faced it lots on my alt account using 4-5-1 V and i never had a problem. Problem poses if you further motivate your AML/AMR making them act as almost lateral STs, or when you don't motivate your DL/DR s . That way you create a huge gape between DL and AML and DR and AMR and that's exactly where the motivated MR/ML play the ball. But having full pitch pressing with red arrows on defense and none (or blue) on AMs prevents that.