I would try to attack over the uncovered wing. Based on the formation I would suspect he attacks over the center.
With one striker 3 defenders and a defensive mid you should get stability there. 3 midfielders to cover his four: ML-MC-MR and 2 strikers.
That makes it a 3N-DMC-3W-2. As tactics: zonal defense, no offside trap, attack through left wing (since he has neither right back nor right midfielder). If he is as strong as you I would suggest normal mentality, mixed passing with pressure own half. Good luck.