Generally players do fine a single square out of position. A MC generally plays well in AMC, DMC, ML, and MR too. Just avoid going crazy and you'll do fine (I limit myself to 3 out of positions players). To answer your question, yes, an AMR would do fine in MR, just know that the way you'd be playing the 4-4-1-1 the players in ML/MR need good "Handling" and "Marking" in the defense category.

4-4-1-1:
DL---DC--DC---DR
------------------
ML---MC-MC---MR
-------AMC-------
--------ST-------

Tactics (adjust to your liking!):

Team Mentality: Normal
Focus Passing: Through the Middle (important)
Pressing Style: Own Half (not important)
Tackling Style: Hard
Passing Style: Short
Marking Style: Zonal

Force Counterattacks: On
Play offside trap: Off (important)