My AML/AMR never play on the flanks in match simulation, even if I put them in the 'red zone'. They are 100+ goals/40+ assists a season between them, they have been comparatively under performing this season, because of where they are playing, according to the match simulation.
Finally got the wingers to play on the wings. They need to be placed as far to the left in their 'boxes' as possible, with the corner of the shirt sleeve touching the border, so effectively with a 'Down arrow'... What a palaver.
Any formation or tactics advice given is based purely on experience with my teams...