No we rotate our squad just to counter others formation. That is, if I need to play town AMC and no DMC in the next match, only then I remove my DMC and bring in another AMC. Otherwise, I rotate squad to play friendly to win boosters as I avoid playing my best players in friendlies as they may get injured. But it depends on u and or style of play. If u have 2 good AMC, suppose, and u can't play both together due to ur formation or other team players, then u can play one in one match and the other one in another.
All the best with or team.