He must be using some good tactical orders as I've had pretty good results using ND against his formation. Bear in mind you had a player out of position playing at DMC - a critical position if defending against a central spine formation. ...and red arrows on DL/DR - not something I ever use. The one on your right-back allowed his left-winger to get behind him - compare the two ratings...
Any formation or tactics advice given is based purely on experience with my teams...
Why you don't look on how much his GK make a saves and also your GK, his GK make 6 saves and your GK only 1
Nothing strange if your DL+R score, last season I also play 442ND and my DL+R score a lot, but I don't use red arrow on MC + AMC + ST, no blue on DMC + DC, only red on DL+R and also play mix focus, not through the middle.
Try to understand, stronger team not make you win every game.