depends on the opponent. The more rigid they are, the more likely I am to use orders that aren't as neutral because it's a pretty safe bet they won't be changing anything tactically.
On my server (around my level) most managers are tactically rigid and play attacking, long passes and high press. So I usually just play high press defense (Park and Drive) default. defense/flanks/mixed or long/on/high/normal/zonal/off.
But if it's an active manager that's flexible, something like normal/flanks/mixed/off/high/normal/zonal/off would be best, as it's balanced. If heavy underdog, maybe go with tactics more towards the polls, like hard attacking/defending etc... I would think if normal is most balanced, the more extreme orders would increase the odds of of an upset (or getting completely annihilated) if i'm underdog.